By Stella Nikolaou, Clinical Research Fellow, The Royal Marsden Hospital and Imperial College London and Shahnawaz Rasheed, Consultant Surgeon, The Royal Marsden Hospital and Senior Lecturer, Imperial College London.
Worldwide, there are more than 5 million people who die from violence and injury1. Uncontrolled bleeding causes more than 40% of trauma-related deaths1. More than 530 000 women die each year during pregnancy, childbirth or post partum and 99% of these women are in low and middle-income countries with severe bleeding being the commonest cause of death1. Safe and affordable surgery, therefore relies on access to a sufficient volume of blood which can be safely transfused2.