{"id":2520,"date":"2018-05-31T09:25:02","date_gmt":"2018-05-31T09:25:02","guid":{"rendered":"https:\/\/blogs-staging.imperial.ac.uk\/surgeryandcancer\/?p=2520"},"modified":"2018-05-31T09:25:03","modified_gmt":"2018-05-31T09:25:03","slug":"4th-new-perspectives-in-drug-metabolism-and-pharmacokinetics","status":"publish","type":"post","link":"https:\/\/blogs-staging.imperial.ac.uk\/surgeryandcancer\/2018\/05\/31\/4th-new-perspectives-in-drug-metabolism-and-pharmacokinetics\/","title":{"rendered":"4th New Perspectives in Drug Metabolism and Pharmacokinetics"},"content":{"rendered":"<figure id=\"attachment_2522\" aria-describedby=\"caption-attachment-2522\" style=\"width: 640px\" class=\"wp-caption aligncenter\"><a href=\"https:\/\/blogs-staging.imperial.ac.uk\/surgeryandcancer\/2018\/05\/31\/4th-new-perspectives-in-drug-metabolism-and-pharmacokinetics\/30b455be-c522-4702-abdc-6f02fef76883\/\" rel=\"attachment wp-att-2522\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"822\" class=\"wp-image-2522 size-large\" src=\"https:\/\/blogs-staging.imperial.ac.uk\/surgeryandcancer\/files\/2018\/05\/30b455be-c522-4702-abdc-6f02fef76883-1024x822.jpg\" alt=\"\" \/><\/a><figcaption id=\"caption-attachment-2522\" class=\"wp-caption-text\">Pictured: Pete Bradshaw, final year PhD student studying aromatic amide hydrolysis, presenting his work.<\/figcaption><\/figure>\n<p>This jointly organised\u00a0meeting of the RSC BMCS, DMDG and Drug Metabolism Group, was held at Royal Society of Chemistry in Burlington House on 21-22 May 2018.<\/p>\n<p>Over the two-day event, participants heard about recent research in drug discovery and development, spanning a wide range of topics; main sessions covered the broad areas of reactive metabolites and adverse reactions, chemical aspects of large molecules development, and medicinal chemistry approaches to improved metabolism, as well as a \u2018hot topics\u2019 session.<\/p>\n<p>A keynote address by Douglas Spracklin (Pfizer, USA) set the scene for the meeting, providing an overview of the strategies and methods that have been developed for efficient, biocatalytic lead diversification.<br \/>\nGiven the location of the meeting, a fitting central theme of the meeting was the need to understand the fundamental chemical principles underlying the observed biology, whether that be related to compound properties, kinetics, quantitation, or identification.<\/p>\n<p>In addition to the platform presentations, participants had meeting-long access to the scientific posters and exhibitor stands, which continued this narrative and demonstrated the diversity and high level of activity in the DMPK arena.<\/p>\n<p><strong>Toby Athersuch<\/strong><br \/>\n<strong>Drug Metabolism Group (DMG) Chairman<\/strong><\/p>\n<p>The 5th New Perspectives in DMPK conference will take place in early 2020. Details will be made available via the RSC BMCS, DMDG and DMG websites in mid 2019.<\/p>\n<p><a href=\"http:\/\/www.rsc.org\/Membership\/Networking\/InterestGroups\/BMCS\">www.rsc.org\/Membership\/Networking\/InterestGroups\/BMCS<\/a><br \/>\n<a href=\"http:\/\/www.thedrugmetabolismgroup.com\">www.thedrugmetabolismgroup.com<\/a><br \/>\n<a href=\"http:\/\/www.dmdg.org\">www.dmdg.org<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>This jointly organised\u00a0meeting of the RSC BMCS, DMDG and Drug Metabolism Group, was held at Royal Society of Chemistry in Burlington House on 21-22 May 2018. Over the two-day event, participants heard about recent research in drug discovery and development, spanning a wide range of topics; main sessions covered the broad areas of reactive metabolites [&hellip;]<\/p>\n","protected":false},"author":600,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-2520","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/blogs-staging.imperial.ac.uk\/surgeryandcancer\/wp-json\/wp\/v2\/posts\/2520","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs-staging.imperial.ac.uk\/surgeryandcancer\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs-staging.imperial.ac.uk\/surgeryandcancer\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs-staging.imperial.ac.uk\/surgeryandcancer\/wp-json\/wp\/v2\/users\/600"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs-staging.imperial.ac.uk\/surgeryandcancer\/wp-json\/wp\/v2\/comments?post=2520"}],"version-history":[{"count":4,"href":"https:\/\/blogs-staging.imperial.ac.uk\/surgeryandcancer\/wp-json\/wp\/v2\/posts\/2520\/revisions"}],"predecessor-version":[{"id":2525,"href":"https:\/\/blogs-staging.imperial.ac.uk\/surgeryandcancer\/wp-json\/wp\/v2\/posts\/2520\/revisions\/2525"}],"wp:attachment":[{"href":"https:\/\/blogs-staging.imperial.ac.uk\/surgeryandcancer\/wp-json\/wp\/v2\/media?parent=2520"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs-staging.imperial.ac.uk\/surgeryandcancer\/wp-json\/wp\/v2\/categories?post=2520"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs-staging.imperial.ac.uk\/surgeryandcancer\/wp-json\/wp\/v2\/tags?post=2520"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}