{"id":108,"date":"2022-05-15T08:57:07","date_gmt":"2022-05-15T08:57:07","guid":{"rendered":"https:\/\/blogs-staging.imperial.ac.uk\/my-path\/?p=108"},"modified":"2022-05-15T15:20:42","modified_gmt":"2022-05-15T15:20:42","slug":"tertiary-syphilis","status":"publish","type":"post","link":"https:\/\/blogs-staging.imperial.ac.uk\/my-path\/2022\/05\/15\/tertiary-syphilis\/","title":{"rendered":"Syphilitic Aortic Aneurysm"},"content":{"rendered":"<p><strong>Tertiary syphilis:<\/strong><br \/>\n1.\tcardiovascular syphilis,<br \/>\n2.\tneurosyphilis (meningovascular syphilis, tabes dorsalis and general paralysis of the insane ).<br \/>\n3.\t\u201cbenign \u201ctertiary syphilis.<br \/>\nAfter 5 years in 1\/3rd of untreated patient<\/p>\n<p><strong>Cardiovascular syphilis<\/strong><br \/>\n80% of cases of  tertiary syphilis<br \/>\nProbably immune mediated<br \/>\nEndarteritis of the vaso vasorum leading to fibrosis of the media<br \/>\nIncreasing dilatation of the  aortic root (leading to aortic incompetence) and arch (leading to an aneurysm).<br \/>\nAlso, obstruction of the coronary artery ostia leading to ischaemia<\/p>\n<p><strong>Other causes of aortitis:<\/strong><br \/>\n1.\tGiant cell arteritis (&gt;50).<br \/>\n2.\tTakayasu\u2019s arteritis  (&lt;50).<br \/>\nBoth may involve the eye.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"156\" src=\"https:\/\/blogs-staging.imperial.ac.uk\/my-path\/files\/2022\/05\/Picture-1-300x156.jpg\" alt=\"\" class=\"alignnone size-medium wp-image-109\" \/><\/p>\n<p>https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMicm2110835<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"230\" src=\"https:\/\/blogs-staging.imperial.ac.uk\/my-path\/files\/2022\/05\/FSzTKmoWUAIBt90-300x230.jpeg\" alt=\"\" class=\"alignnone size-medium wp-image-114\" \/><\/p>\n<p>Avraham Z. Cooper, MD @AvrahamCooperMD<br \/>\n&#8220;Pulsatile chest swelling &#x27a1;&#xfe0f; HUGE aortic aneurysm from tertiary syphilis.&#8221;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tertiary syphilis: 1. cardiovascular syphilis, 2. neurosyphilis (meningovascular syphilis, tabes dorsalis and general paralysis of the insane ). 3. \u201cbenign \u201ctertiary syphilis. After 5 years in 1\/3rd of untreated patient Cardiovascular syphilis 80% of cases of tertiary syphilis Probably immune mediated Endarteritis of the vaso vasorum leading to fibrosis of the media Increasing dilatation of [&hellip;]<\/p>\n","protected":false},"author":1119,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[290089,318391,247574],"tags":[],"class_list":["post-108","post","type-post","status-publish","format-standard","hentry","category-cardiac-pathology","category-nejm","category-year-5"],"_links":{"self":[{"href":"https:\/\/blogs-staging.imperial.ac.uk\/my-path\/wp-json\/wp\/v2\/posts\/108","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs-staging.imperial.ac.uk\/my-path\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs-staging.imperial.ac.uk\/my-path\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs-staging.imperial.ac.uk\/my-path\/wp-json\/wp\/v2\/users\/1119"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs-staging.imperial.ac.uk\/my-path\/wp-json\/wp\/v2\/comments?post=108"}],"version-history":[{"count":5,"href":"https:\/\/blogs-staging.imperial.ac.uk\/my-path\/wp-json\/wp\/v2\/posts\/108\/revisions"}],"predecessor-version":[{"id":118,"href":"https:\/\/blogs-staging.imperial.ac.uk\/my-path\/wp-json\/wp\/v2\/posts\/108\/revisions\/118"}],"wp:attachment":[{"href":"https:\/\/blogs-staging.imperial.ac.uk\/my-path\/wp-json\/wp\/v2\/media?parent=108"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs-staging.imperial.ac.uk\/my-path\/wp-json\/wp\/v2\/categories?post=108"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs-staging.imperial.ac.uk\/my-path\/wp-json\/wp\/v2\/tags?post=108"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}