Category: Department of Surgery and Cancer

The Bionic Radiologist: can artificial intelligence enhance human detection of bone disease?

artificial intelligence bone disease

Originally published on the NIHR Blog and reproduced here with permission, Professor Andrea Rockall, Clinical Chair of Radiology at Imperial, provides an insight into whether AI can enhance human detection of bone disease.


Myeloma is a disease that affects the skeleton and can be difficult to pick up at an early stage because symptoms are often quite vague. People who suffer from myeloma may be generally more tired than usual due to anaemia and may have aching bones. As the disease progresses, thinning of the bones may result in fractures, particularly of the spine, and this may be the first time that the diagnosis is picked up. The kidneys may also be affected due to an increase in myeloma proteins circulating in the bloodstream getting caught up in the delicate kidney tubules that filter the blood. If the disease is picked up early, some of these problems can be prevented. (more…)

Could the EndoBarrier be the next weapon of mass reduction?

Endobarrier

In this post, Dr Aruchuna Mohanaruban tackles the most asked questions about the EndoBarrier – a medical device for the treatment of type 2 diabetes and obesity.


UK obesity rates have continued to rise at an alarming rate, with figures higher than any other developed nation. Strongly associated with obesity is the increased susceptibility to developing type 2 diabetes (T2DM) which currently affects 3.2 million of the UK population. Bariatric surgery – a type of surgery aimed at inducing weight loss – usually by altering the stomach and/or intestines has revolutionised the treatment of these conditions and can lead to a 60% remission in diabetes. However, with demand for this type of surgery outstripping supply, there is a greater need to develop non-surgical alternatives to combat the ever-rising obesity and diabetes epidemic. (more…)

“You don’t defibrillate asystole…” and other arguments with creatives

Dr Christopher Peters provides an insight into life behind the scenes as a TV medical advisor for leading programmes such as Eastenders and Holby City.


It is a favourite pastime of anyone who works in healthcare to scoff at the mistakes we see when medicine is portrayed on film. From the back-to-front chest X-ray on Scrubs to the miraculous success rates of chest compressions in soaps we love to mock. However, for the last four years I have been working with various TV programmes to try to inject a degree of realism without dampening the drama.

This started with Holby City when I helped out on set, making sure that operating scenes looked realistic and that the actors could pass off as surgeons. This was my introduction to the tension between realism and plot. Being a medical drama, Holby had the budget and resources to try and get things right, but even they couldn’t keep viewers interested if they showed a lovely routine list of day cases where nothing goes wrong! (more…)

Would you give the gift of a kidney to a stranger in need?

Kidney donations stranger

It is the season of giving, so we look at how kidney donations from strangers are giving kidney disease patients a second chance at life. 


As far as generous Christmas presents go, donating your kidney seems for many at the extreme end. However, for a few lucky kidney disease patients, this is the gift of a lifetime. Known as unspecified or non-directed altruistic kidney donation, this form of live organ donation is on the rise, and could potentially wipe the waiting list if more stepped forward. I met Frank Dor, a consultant transplant surgeon and Head of Transplantation at Imperial College Healthcare NHS Trust, who has carried out hundreds of live organ donations. (more…)

World AIDS Day: Professor Mark Bower on HIV-related cancers

World AIDS Day

To mark World AIDS Day 2017, we have published a series of blog posts to highlight the important and varied research that takes places at Imperial. Three experts from Faculty of Medicine share their interest in HIV/AIDS which spans from the elusive vaccine to the economics of the epidemic.

World AIDS Day takes place annually on 1 December as an opportunity for people worldwide to unite in the fight against HIV and to show support for people living with HIV/AIDS.


Oncologist turned HIV expert

As a medical oncologist at Chelsea and Westminster Hospital, I specialise in the treatment of HIV-related cancers at the National Centre for HIV Malignancy – Europe’s largest research and treatment institute for these cancers. Over the last 25 years, I have seen an astonishing improvement in the outcomes of people diagnosed with both HIV and cancer, so that patients under my care with most HIV associated cancers now have the same overall survival as HIV negative patients. (more…)

How a little Mo effort can make a big difference

To mark Movember, PhD student Akifumi Shibakawa explains how Movember cash is funding prostate cancer research at Imperial and how to get involved in the fundraising. 


It’s that time of the year again, when men grow moustaches around the globe. It all started in 2003, when two guys in Australia had the idea to make moustache-growing fashionable again. For a greater cause, they made this campaign about men’s health and established the Movember Foundation. As you may know, the campaign became an international phenomenon, attracting over 300,000 participants in more than 20 countries in 2016. (more…)

The Pathology Museum’s top treasures

Pathology museum

Tucked away in Charing Cross Hospital is Imperial’s best-kept secret: The Pathology Museum. Housing a 2,500-strong collection of anatomical specimens, the Pathology Museum contains some rare and unique artefacts dating from 1888, including the first hysterectomy performed in England.


Carefully curated by the Human Anatomy Unit (HAU), the specimens are grouped together based on organ systems, creating a well-arranged display of human pathology. The museum’s primary function is to help educate medical and biomedical students to diagnose diseases. The museum also hosts a number of conference and short courses in pathology for experienced professionals.

The collection incorporates specimens from across the Faculty of Medicine’s founding medical schools, there are an astonishing 4,000 further specimens not on display. This vast archive provides a snapshot of the historical foundations of the medical school. (more…)

Think peach: the true symbol of breast cancer awareness

 Breast cancer awareness

Breast cancer researcher, Dr Luca Magnani, looks beyond the pink ribbon campaign to find the true symbol of breast cancer awareness.


It’s that time of year once again: Instagram and Twitter will adopt a light shade of pink, companies will adorn their products with the ubiquitous pink ribbon, all to remind us of Breast Cancer Awareness Month. To a breast cancer scientist such as myself, October always brings out ambiguous emotions. On one side, it serves as a reminder of all the great research and results that we have achieved. Statistics show that things are getting better for many women, as mortality rates have halved in the last 20 years. October also prompts many of us to remember that there is nothing better than prevention when talking about breast cancer. Early screening measures have revolutionised outcomes for women; it’s very likely that almost 50% of the lives that were saved depended on catching the cancer earlier. (more…)

One small step in wearable tech: one giant leap in osteoarthritis detection and management

Dr Enrica Papi a post-doctoral research associate looks at how the rise of wearable tech could play a role in osteoarthritis detection and management.


When deciding what to do in life, it was clear that I wanted to help people live better, however becoming a doctor wasn’t for me. I found my way through studying biomedical engineering, which developed my passion for the biomechanics of human movement. I see this as a means to understanding the underlying mechanisms of musculoskeletal disease. Through detailed assessment of patients’ movement function we can understand the implications of disease progression and propose solutions to mitigate the developing disorders. To a curious mind like mine, this is a fascinating way to achieve my aspirations. The idea of being able to find explanations as to why things happen to our bodies is amazing and the fact that it can improve people’s quality of life makes it all the more satisfying. (more…)

How to PREPARE for surgery and speed your recovery

surgery recovery

Originally published on the Imperial College Healthcare NHS Trust blog, here clinical nurse specialist Venetia Wynter-Blyth explains how the programme helps patients adopt the good habits needed to aid their recovery.


All types of surgery require preparation and, afterwards, recovery time. But according to the oesophago-gastric cancer team at Imperial College Healthcare NHS Trust, undergoing major surgery is like running a marathon. The PREPARE for Surgery programme, designed by the team, ‘trains’ patients for surgery based on their individual needs. It looks at different factors important to focus on before and after a procedure, including physical activity, diet, psychological wellbeing and medication management.  (more…)