Tag: biological engineering

Why the future of bioengineering is so bright

Sunset over Los Angeles from Griffiths Observatory
Sunset over Los Angeles from Griffiths Observatory

The last stop on my US tour was the inspirational California Institute of Technology. Based in Pasadena, Caltech has been reported as the top university in the world for the last three years in the Times Higher Education University Global Rankings. Although these rankings usually focus on a particular area I would agree that there is something pretty special about Caltech. The Caltech outlook was epitomized for me by Professor Frances Arnold who said they are not just training students to become scientists or engineers, they are training them to become Nobel Prize winners.

With that ambition laid on the table it was refreshing to hear such a senior academic speak so enthusiastically about her research and the development of her research over time from her mechanical & aerospace engineering roots through chemical engineering to her current research on protein engineering.

Broad the home of the Division of Biology and Biological Engineering at Caltech
Broad the home of the Division of Biology and Biological Engineering at Caltech

I also met with Professor Michael Elowitz while at Caltech, a physicist by background Michael now works in synthetic and systems biology and is the Executive Director of Bioengineering in the Division of Biology and Biological Engineering.

I was interested in the naming of the division as this was the first time that bioengineering had been partnered with biology. Although the meaning of biological engineering at Caltech does have similar origins to MIT. Rather than use any of the MIT or Imperial-inspired triangle or square analogies Professor Elowitz sees biology and bioengineering as two sides of the same coin.

“It’s not the things that will be found out, but the way we approach the problems and the solutions we will come up with.”~ Professor Michael Elowitz

An example of this is Professor Michael Elowitz’s circuit approach to molecular biology. It’s not what the molecules do in isolation it’s what they do in combination, in a physiological environment that he finds most fascinating. With medicine the greatest successes will not be discovering the origins of disease, but will be creating new interventions to assist or in a more ideal world prevent disease before it starts.

“Intellectuals solve problems, geniuses prevent them.” ~Albert Einstein

While speaking to Professor Michael Elowitz  he mentioned Sean R. Eddy’s paper about “Antedisciplinary” Science, published in 2005.  I would recommend reading this article as although now nearly ten years on a lot of the ideas still hold true today. Caltech also supports and encourages individual interdisciplinary people, there seemed to be a lot of fluidity between the loose Department and division structure with academics given the space to follow their research interests. An environment, which given the calibre of the students that attend Caltech, is a healthy and inspiring environment to be in.  

“When I think of new fields in science that have been opened, I don’t think of interdisciplinary teams combining existing skills to solve a defined problem—I think of single interdisciplinary people inventing new ways to look at the world.”~ Sean R. Eddy

In my opinion bioengineers are a prime example of ‘interdisciplinary people’, and the field attracts equally ‘interdisciplinary people’ from other scientific or engineering backgrounds. We need to utilise the tools, technology and techniques that we have and will create for bioengineering to fulfill its potential contribution to society.

This trip has made me wonder what the future bioengineering department would look like. It’s hard to say because the options are endless. I had thought that as bioengineering matures as a discipline bioengineering graduates will fill up our bioengineering departments. I don’t think that will entirely be the case though. As Professor Frances Arnold talked me through her journey to her current protein engineering research something consistently came up in her explanation. “It’s exciting.” Researchers from all fields will be pulled to bioengineering research because it’s intellectually exciting. This diversity doesn’t dilute, it only enriches the discipline.

I was also interested to hear that 15% of the undergraduates at Caltech are majoring in bioengineering or chemical engineering, with students who previously would have chosen biology or mechanical engineering in particular attracted to the new major.

“We are creating the future of engineering, not following it.”~ Professor Frances Arnold

This trip has certainly fueled my excitement, and I believe that now is the time for bioengineering to cement it’s central engineering role, whether it’s from the foundations of biology or a broader combination of sciences, bioengineering is here to stay.

‘Til next post

Jenna

The beginning…

Monday February 24th marked the first day of my two week tour of US bioengineering institutions and a fascinating start it has been.

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I began my day at MIT where Professor Doug Lauffenburger had arranged a comprehensive schedule of meetings for me to gain an insight about bioengineering at MIT.

At MIT they approach bioengineering from the biological angle, as Professor Lauffenburger described to me in the morning each engineering discipline has a scientific knowledge base with a range of applications. However bioengineering has traditionally approached it differently with a broad foundation in a range of disciplines including maths, physics, chemistry and biology but with one primary application area of healthcare/ medicine.

This was an interesting approach that got me thinking about where Imperial fitted within these two approaches. In my opinion Imperial views bioengineering in a more ‘square’ than triangular approach with a broad foundation of science and engineering and a broad range of applications.

Although I sense a lot of similarities between Imperial and MIT the distinct difference between the two institutions was the biological basis of the undergraduate course at MIT compared to the engineering basis of the undergraduate course at Imperial.

While at MIT I also met with Professor Roger Kamm and Professor Ron Weiss, two professors who represent distinctly different areas of bioengineering. Professor Kamm biomechanics and Professor Weiss synthetic biology.

What struck me from the meeting with Professor Weiss was the recognised importance of design in engineering and particularly synthetic and systems biology. Weiss is also one half of the two professor team jointly teaching a course at MIT and UC Berkeley with Professor Adam Arkin via alternating video link.

Professor Kamm introduced the Institute for Medical Engineering and Health (IMES) to me as the MIT equivalent to the Institute of Biomedical Engineering (IBME) at Imperial College London. “IMES aims to accelerate innovation across a spectrum of activities that span discovery, design, and delivery of new medical devices and products” whereas “IBME draws together scientists, medics and engineers to apply their extensive expertise to create revolutionary progress in medical diagnosis and treatment.”

While at MIT I also met with Dan Darling the Industry Outreach Coordinator, Dr Agi Stachowiak and Dr Natalie Kuldell. What was clear from these meetings is the clear comparisons between Imperial and MIT, from provision of summer school programmes, social media management and industry engagement to embedding communication and other transferable skills within academic courses and having vision for development of outreach/ engagement activities. Including the importance of high school education on the development of undergraduate courses.

The second Institutional stop on the tour was Boston University (BU) and their Chair of the Department Professor Solomon Eisenberg. BU have a different approach to bioengineering to MIT, with a biomedical engineering focus and a high number of undergraduate students (545 in 2012-13) compared to the 178 biological engineering majors at MIT and 293 biomedical engineering undergraduates at Imperial.

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The BU Department of Bioengineering is also one of the earliest with foundations in the 1966, another interesting observation about the Department at BU is that it is only one of three engineering Departments at Boston University. The others being Electrical and Computer Engineering and Mechanical Engineering. The Department was also awarded one of the three Whitaker Foundation Leadership Awards back in 1996 alongside Johns Hopkins University and University of California- San Diego.

The Department of Bioengineering at BU also runs a course on Advanced Biomedical Design and Development Project as part of their postgraduate MEng in biomedical engineering. In this course students are immersed in the clinical environment for 6-8 weeks to gain an insight into the clinical area they will be developing a product for.

All in all its been a fascinating first day, lots of parallels with bioengineering in the UK and some expected differences. I for one am excited to see what further insight the rest of the trip has to offer.

‘Til next post
Jenna

Hello world!

The home of Imperial College London Bioengineering
The home of Imperial College London Bioengineering

Hello readers

Welcome to the Imperial Bioengineering Blog. This blog will evolve to cover a whole range of bioengineering, so if you are interested in finding out more about the research, innovations and generally cool stuff that is going on in the Department of Bioengineering at Imperial College London and the discipline more globally then this is the blog for you.

But why, you may wonder has the Department decided to start a blog now? There is a very good reason for this, which I will dedicate the rest of this first blog to answering.

Bioengineering is the fastest growing discipline of engineering. Data from the USA shows that Biomedical Engineering is the “Best job in America” with 10-year job growth of 61.7% and a good median and top pay. But it is more than the job prospects and salary that make biomedical engineering such an attractive profession. Christine Schmidt, a professor of biomedical engineering at the University of Florida was quoted in the CNN piece as saying “You can impact so many lives by creating technology that will repair a hip or help repair eyesight or allow somebody to breathe better.”

It is this that make biomedical engineering such an attractive, necessary and fast growing discipline. Now you have probably noticed I have used both biomedical engineering and bioengineering interchangeably in the last paragraph. I think it is useful in this first post to define what we mean by bioengineering in the Department of Bioengineering here at Imperial.

Bioengineering is the application of engineering principles to biological or medical problems. 

In the Department we go on to further define the three pillars of bioengineering:

Biomedical Engineering Developing devices, techniques and interventions for human health.

Biological Engineering Solving problems related to the life sciences and their applications for health.

Biomimetics Using the structures and functions of living organisms as models for the design and engineering of materials and machines.

Biomedical engineering is also the “most valuable College major” another US statistic, this time from Forbes. Which brings me onto the catalyst for this blog, my imminent trip to the USA to find out more about bioengineering over there.

I fly out on the 23rd February to America for two weeks of meetings to find out more from those at the centre of the discipline. The first few posts on this blog will be about what I learn as I meet some incredible bioengineers all around the US, beginning in Boston and travelling to New York, Baltimore, San Francisco and finishing up in Los Angeles. Please do comment on the blogs especially if you have questions or would like to know more. Below I have listed the Universities I will be visiting on my travels, to those reading this who I will be meeting, I look forward to seeing you soon, for others I look forward to telling you all about it.

  • Massachusetts Institute of Technology
  • Boston University
  • Northeastern University
  • Columbia University
  • Johns Hopkins University
  • Biomedical Engineering Society
  • University of California- Davis
  • Stanford University
  • University of California- Berkeley
  • University of California Los Angeles
  • University of Southern California
  • California Institute of Technology

‘Til next post.

Jenna

Outreach Manager, Department of Bioengineering, Imperial College London.